Duovir Tablet

Duovir Tablet is a treatment for the HIV virus developed by Cipla.

Effects of Duovir Tablet

Zidovudine, the main ingredient in Duovir, is phosphorylated in HIV-infected cells and becomes the active triphosphorylated form, which inhibits HIV reverse transcriptase.

It exhibits an antiviral effect that is approximately 100 times stronger and more selective than DNA polymerase.

Lamivudine, the main ingredient in Duovir, inhibits the reverse transcriptase of hepatitis B virus and HIV types 1 and 2.

It has the characteristic of being rapidly absorbed into the body, and its circulation rate in the body is high, at over 80%.

The combination of these two ingredients is said to have a highly synergistic effect against the HIV virus, stopping the elongation of the DNA chain of the HIV virus and inhibiting the proliferation of the virus , thereby reducing the virus and providing immunity. Your strength will be restored.

Although it is difficult to kill the HIV virus, it is effective in slowing the worsening and progression of symptoms.

others

Zidovudine, one of the main ingredients, may cause bone marrow suppression, so blood tests should be performed frequently.

People with chronic hepatitis B should be careful when discontinuing lamivudine, as discontinuation of lamivudine may cause the chronic hepatitis B to flare up.

How to take Duovir Tablet

Timing of taking

Duovir should be taken at the same time every day to keep blood levels of the ingredients constant.

Estimated dosage

Take 1 tablet at a time, twice a day.

Duovir is a combination drug containing fixed doses of zidovudine and lamivudine, so if you need to adjust the dosage of zidovudine or lamivudine, please take each component separately.

Some people take double or triple the prescribed dose at once in order to expect a strong effect, but this does not mean that the effect will be strong.

If anemia or neutropenia is confirmed during the treatment period, please stop taking the drug and adjust the dosage and administration using zidovudine or lamivudine.

Recommended dose

It is usually recommended for adults to take 1 tablet orally twice a day.

Please consult your doctor before taking this medicine as it may need to be used in conjunction with other HIV virus treatments.

People who cannot take Duovir

• Those who have a history of hypersensitivity when taking medicines containing zidovudine or lamivudine
• Those whose neutrophil count has decreased to less than 750/mm3 or the hemoglobin level has decreased to less than 7.5 g/dL
• Those who are taking ibuprofen
• Those who are pregnant or may be pregnant,
• Those who are breastfeeding

Side effects of Duovir Tablet

Main side effects

Main side effects include gastrointestinal disorders, malaise, fever, liver dysfunction, rash, and dizziness.

Serious side effects include blood disorders, lactic acidosis, pancreatitis, rhabdomyolysis, neuropathy, confusion, convulsions, and epileptiform seizures.

If any of these symptoms occur, immediately stop taking the drug and consult a doctor.

Drugs prohibited for concomitant use

Contraindications for concomitant use

Contraindicated drugs are drugs that are incompatible with Duovir and cannot be taken together.

• Ibuprofen may increase bleeding tendency in people with hemophilia.

Caution when used together

• Precautions for concomitant use are drugs that require caution when used in combination with Duovir.
• The side effects of pentamidine, pyrimethamine, flucytosine, and other zidovudines may be exacerbated.
• There is a report that the circulation rate of probenecid zidovudine has been reduced by about 1/3 and the half-life has been extended by about 1.5 times.
• It has been reported that the maximum blood concentration of fluconazole and phosfluconazole zidovudine increases by 84%.
• In addition to these, there are other drugs that should be taken with caution, so please check the reference site.

Other Sexual Wellness Medicine

• Forcan 150mg
• Forcan 200mg
• Keto Cream 15g
• Levoflox 250mg

Storage method

• Store in a cool, dry place away from direct sunlight.
• Please store out of reach of small children.
• Please do not replace the container as it may cause accidental ingestion or the quality may change.
• If you want to take the remainder of one packet, store it as much as possible to avoid exposure to air, and take it within 2 days.
• Do not take or use the product after the indicated expiry date.